

Plugins Several enhancements of the plugins previously suggested were implemented : - option to browse images in a directory - selection of the dimension for hyperstack browsing - "Add new category" button for the "button" and "checkbox" plugins - pop-up with keyboard shortcut message for buttons in the "button" plugin - "run measure" checkbox was moved to the initial configuration window - annotations are appended to any active table for ImageJ > 1.53g - Add a checkbox option to recover categories from an active table

Both authors are former employees of DITABIS AG, Pforzheim, Germany and as of 2021 employees of ACQUIFER Imaging GmbH, Heidelberg, Germany exclusively. Uses cases section was simplified, there is no more dedicated paragraphs for the sunburst chart and deep learning - Previous Figure 4 is now available as Supplementary Figure 4 on Zenodo - A new data-visualization Fiji plugin for pie chart visualization was implemented (see new supplementary Figure 2) - the DOI link to Zenodo was updated to always point to the latest version - The ‘competing interest’ statement was updated to reflect the current positions of Jochen Gehrig and Laurent Thomas. Manuscript - the introduction includes a brief review of existing annotation solutions and their limitations - Figure 1-3 have been updated to reflect the new plugin interfaces - Figure 4 has been replaced with an overview figure of the possible data-visualizations and applications - similarly the
